Celiac Disease (CD), is also known as Celiac Sprue and
Gluten-Sensitive Enteropathy. CD is a chronic digestive disorder caused
by a toxic reaction to the ingestion of "gluten". Gluten is group of
proteins that is found in all forms of wheat, including durum,
semolina, spelt, rye, oats, barley, and related grain hybrids such as
triticale and kamut. CD has also been called "The Irish Disease"
because it is genetic and most commonly found in those of Celtic
origin. This disease affects about 1:50 persons in Ireland and recent
studies show that it affects 1:250 in the United States.
Cause
The
cause of CD is unknown. It appears to be strongly associated with a
group of genes on Chromosome 6. These genes (HLA class II) are involved
in regulations of the body's altered immune response to the gluten
protein fractions. In fact, the allergic person may not even need the
whole gliaden protein to be present. Current research shows that even
an amino acid sequence as small as 4 Amino Acids may elicit the
allergic response. CD is triggered during any stage of life by unknown
environmental factors such as stress, physical trauma, viral infection,
pregnancy, or surgery.
Symptoms
This
disease is an autoimmune disease. The site of this reaction is the
small intestine, the function of which is to digest and absorb
nutrients. The absorptive surface of the small intestine are damaged or
destroyed. This means the body is unable to absorb basic nutrients. The
patient may have chronic abdominal pain, cramping, and diarrhea. If
left untreated, the results can be life threatening.
Long-term
disorders that can result from CD: bone disease, osteoporosis, internal
hemorrhage resulting from Vitamin K deficiency, nervous system
disorders due to nutritional deficiencies, pancreatic disease,
intestinal lymphomas and other cancers, other food sensitivities may
arise, such as lactose intolerance.
Diagnosis
This
disease is very difficult to diagnose. However, there are useful tests
now available. Antibody tests are used to identify people who may be at
risk. A biopsy of the small intestine is the only sure diagnosis: the
results are classic - flattened or absent villi of the small intestine.
The physician would then recommend a gluten-free diet and monitor the
patient.
Cure
There is no known cure.
The primary treatment is dietary; life-long adherence to a gluten-free
diet. When the toxic proteins are removed, the bowel will heal itself,
nutrients will be absorbed again, and health will return. The challenge
to the CD patient is to learn to carefully read labels to find sources
of hidden gluten. It can be in soups, salad dressings, processed foods,
soy sauce, licorice.
There are several support groups
that provide a tremendous service to CD patients. For further
questions, please visit the Celiac Disease Foundation's website (www.celiac.org/cdf).
Glutenfreeda Online Cooking Magazine is another excellent source of information and recipes for gluten-free cooking.
Dietitian's Word of Warning
If
you feel you may have a food allergy, please consult a doctor and
request a referral to a local dietitian. It is generally a very bad
idea to practice medicine without a license. Similarly, it is extremely
risky to arbitrarily eliminate entire food groups from your diet for
long periods of time. Nutritional deficiency and a general weakening of
the immune is system are the usual results.